Guineapigpolyclonalantibody
- Size:
- 100µl
- Formulation:
- Affinitypurified
- Specificity:
- Rat,Mouse,Human,Non-humanprimate,Rabbit,GuineaPig
- Applications:
- WB1:1,000IHC1:500
- Species:
- GuineaPig
- GeneName:
- RBPMS
- MolecularReference:
- ~24kDa
- CiteThisAntibody:
- PhosphoSolutionsCat#1832-RBPMS,RRID:AB_2492226
Antigen/Purification:Collapse
TheantigenisasyntheticpeptidecorrespondingtoaminoacidresiduesfromtheN-terminalregionoftheratRBPMSsequenceconjugatedtoKLH.
TheantibodyispreparedfromguineapigserumbyaffinitypurificationviachromatographyonanaffinitycolumnpreparedwiththeN-terminalpeptideusedasantigen.
BIOLOGicalSignificance:Collapse
RBPMS(RNAbindingproteinwithmultiplesplicing),alsoknownasHERMES,containsoneRRM(RNArecognitionmotif)domainandbelongstotheRRMfamilyofRNA-bindingproteins.RBPMSexistsasmultiplealternativelysplicedisoformsandisthoughttobindRNA,possIBLyplayingaroleinRNA-relatedevents,suchastranscriptionandtranslation.RNA-bindingproteinsthatarespecifictoretinalganglioncells(RGCs)havebeenpreviouslyidentifiedasexcellentMarkersforRGCs(Kwongetal.,2010).RecentfindingsshowthatantibodiesagainstRBPMSarerobustreagentsthatexclusivelyidentifyRGCsinmultiplemammalianspecies(Rodriguezetal.2014).
Storage
100µlinPBS+0.03%sodiumazide.
Forlongtermstorage–20°Cisrecommendedinundilutedaliquots.Stableat–20°Cforatleast1year.Avoidfreeze/thawcycles.
ProductSpecificReferences
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