4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:神经科学领域的蛋白及抗体
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Functional_antibody > 磷酸溶液/RBPMS抗体,兔/1830-RBPMS/100µl
商品详细磷酸溶液/RBPMS抗体,兔/1830-RBPMS/100µl
磷酸溶液/RBPMS抗体,兔/1830-RBPMS/100µl
磷酸溶液/RBPMS抗体,兔/1830-RBPMS/100µl
商品编号: 1830-RBPMS
品牌: PhosphoSolutions
市场价: ¥4574.70
美元价: 3519.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Rabbitpolyclonalantibody

Size:
100µl
Formulation:
Affinitypurified
Specificity:
Rat,Mouse,Human,Non-humanprimate,Rabbit,GuineaPig
Applications:
WB1:1,000IHC1:500
Species:
Rabbit
GeneName:
RBPMS
MolecularReference:
~24kDa
CiteThisAntibody:
PhosphoSolutionsCat#1830-RBPMS,RRID:AB_2492225
Antigen/Purification:ExpandCollapse

TheantigenisasyntheticpeptidecorrespondingtoaminoacidresiduesfromtheN-terminalregionoftheratRBPMSsequenceconjugatedtoKLH.

Theantibodyispreparedfromrabbitserumbyaffinitypurificationviachromatographyonanaffinitycolumnpreparedwiththepeptideusedasantigen.

BIOLOGicalSignificance:ExpandCollapse

RBPMS(RNAbindingproteinwithmultiplesplicing),alsoknownasHERMES,containsoneRRM(RNArecognitionmotif)domainandbelongstotheRRMfamilyofRNA-bindingproteins.RBPMSexistsasmultiplealternativelysplicedisoformsandisthoughttobindRNA,possIBLyplayingaroleinRNA-relatedevents,suchastranscriptionandtranslation.RNA-bindingproteinsthatarespecifictoretinalganglioncells(RGCs)havebeenpreviouslyidentifiedasexcellentMarkersforRGCs(Kwongetal.,2010).RecentfindingsshowthatantibodiesagainstRBPMSarerobustreagentsthatexclusivelyidentifyRGCsinmultiplemammalianspecies(Rodriguezetal.2014)

Storage

100µlinPBS+0.03%sodiumazide.

Forlongtermstorage–20°Cisrecommendedinundilutedaliquots.Stableat–20°Cforatleast1year.Avoidfreeze/thawcycles.

ProductSpecificReferences

Livne-Bar,I.,Wei,J.,Liu,H.H.,Alqawlaq,S.,Won,G.J.,Tuccitto,A.,Gronert,K.,Flanagan,J.G.andSivak,J.M.,2017.Astrocyte-derivedlipoxinsA4andB4promoteneuroprotectionfromacuteandchronicinjury.TheJournalofClinicalInvestigation,127(12).PMID:29106385

Apara,A.,Galvao,J.,Wang,Y.,Blackmore,M.,Trillo,A.,Iwao,K.,Brown,D.P.,Fernandes,K.A.,Huang,A.,Nguyen,T.andAshouri,M.,2017.KLF9andJNK3InteracttoSuppressAxonRegenerationintheAdultCNS.JournalofNeuroscience,pp.0643-16.PMID:28871032

Chiasseu,M.,Alarcon-Martinez,L.,Belforte,N.,Quintero,H.,Dotigny,F.,Destroismaisons,L.,Velde,C.V.,Panayi,F.,Louis,C.andDiPolo,A.,2017.TauaccumulationintheretinapromotesearlyneuronaldysfunctionandprecedesbrainpathologyinamousemodelofAlzheimer’sdisease.MolecularNeurodegeneration,12(1),p.58.PMID:28774322

Assali,A.,LeMagueresse,C.,Bennis,M.,Nicol,X.,Gaspar,P.andRebsam,A.,RIM1/2arerequiredinretinalganglioncellsfortherefinementofipsilateralaxonsandeye-specificsegregation.ScientificReports.2017,Jun12. PMID:28607399

Joly,S.,Lamoureux,S.andPernet,V.,2017.Non-amyloidogenicprocessingofamyloidbetaprecursorproteinisassociatedwithretinalfunctionimprovementinagingmaleAPPswe/PS1ΔE9mice.NeurobiologyofAging. 2017May;53:181-191.PMID:28262325

Liddelow,S.A.,Guttenplan,K.A.,Clarke,L.E.,Bennett,F.C.,Bohlen,C.J.,Schirmer,L.,Bennett,M.L.,Münch,A.E.,Chung,W.S.,Peterson,T.C.andWilton,D.K.,2017.Neurotoxicreactiveastrocytesareinducedbyactivatedmicroglia.Nature.2017Jan26;541(7638):481-487.PMID:28099414

Hunt,N.C.,Hallam,D.,Karimi,A.,Mellough,C.B.,Chen,J.,Steel,D.H.andLako,M.,2016.3DcultureofhumanpluripotentstemcellsinRGD-alginatehydrogelimprovesretinaltissuedevelopment.ActaBiomaterialia. 2017Feb;49:329-343. PMID:27826002

Chen,L.andGage,P.J.,2016.HeterozygousPitx2NullMiceAccuratelyRecapitulatetheOcularFeaturesofAxenfeld-RiegerSyndromeandCongenitalGlaucoma.InvestigativeOphthalmology&VisualScience,57(11),pp.5023-5030.PMID:27654429

Lim,J.H.A.,Stafford,B.K.,Nguyen,P.L.,Lien,B.V.,Wang,C.,Zukor,K.,He,Z.&Huberman,A.D.(2016).Neuralactivitypromoteslong-distance,target-specificregenerationofadultretinalaxons.NatureNeuroscience.2016Aug;19(8):1073-84.PMID:27399843

Vargas,J.L.C.,Belforte,N.,&DiPolo,A.(2016).TheglialcellmodulatoribudilastattenuatesneuroinflammationandenhancesretinalganglioncellviABIlityinglaucomathroughproteinkinaseAsignaling.Neurobiologyofdisease,93,156-171.PMID:27163643

Shabanzadeh,A.P.,D’onofrio,P.M.,Monnier,P.P.,&Koeberle,P.D.(2015).Targetingcaspase-6andcaspase-8topromoteneuronalsurvivalfollowingischemicstroke.Celldeath&disease,6(11),e1967.PMID:26539914

Vargas,J.L.C.,Osswald,I.K.,Unsain,N.,Aurousseau,M.R.,Barker,P.A.,Bowie,D.,&DiPolo,A.(2015).SolubleTumorNecrosisFactorAlphaPromotesRetinalGanglionCellDeathinGlaucomaviaCalcium-PermeableAMPAReceptorActivation.TheJournalofNeuroscience,35(35),12088-12102.PMID:26338321

Reifler,A.N.,Chervenak,A.P.,Dolikian,M.E.,Benenati,B.A.,Meyers,B.S.,Demertzis,Z.D.,Lynch,A.M.,Li,B.Y.,Wachter,R.D.,Abufarha,F.S.,Dulka,E.A.,Pack,W.,Zhao,X.,&Wong,K.Y.(2015).Theratretinahasfivetypesofganglion-cellphotoreceptors.Experimentaleyeresearch,130,17-28.PMID:25450063

品牌介绍
 有效的抗体!是什么让PhosphoSolutions与众不同?如果我们试图制造一种抗体但它不起作用,我们就把它扔掉。PhosphoSolutions从不出售无法在我们手中发挥作用的抗体。PhosphoSolutions对严格验证标准的承诺可确保内源性蛋白质中的信号清晰,并验证相关产品的磷酸化特异性。PhosphoSolutions致力于重现性。寻找我们的“混合血清”图标。带有此图标的每种抗体均从其自身的血清库中纯化,以确保批次间的一致性。我们保证我们的抗体。如果您不能让抗体在您的申请中发挥作用,我们将提供100% 的退款。在制作定制抗体时,PhosphoSolutions从头到尾提供个性化的客户支持,从肽设计、纯化到表征。