Mousemonoclonalantibody
- Size:
- 100µl
- Formulation:
- ProteinGPurified
- Specificity:
- Rat,Mouse,Human,Bovine
- Applications:
- WB1:2,000IF1:500
- Species:
- Mouse
- MolecularReference:
- ~46/48kDa
- CiteThisAntibody:
- PhosphoSolutionsCat#583-FOX3,RRID:AB_2492096
Antigen/Purification:Collapse
TheantigenisarecombinantproteintakenfromtheN-terminusofhumanFOX3expressedinandpurifiedfromE.Coli.
TheantibodyisProteinGpurifiedfromculturesupernatant.
BIOLOGicalSignificance:Collapse
FOX3,alsoknownasNeuNandhexaribonucleotidebindingprotein3,isaneuron-specificRNAbindingnuclearproteininvolvedintheregulationofpre-mRNAalternativesplicing(Kimetal.,2009).FOX3dependentalternativesplicingofNumbhasrecentlybeenshowntoplayanimportantroleintheprogressionofneuronaldifferentiationduringvertebratedevelopment(Kimetal.,2013).
Storage
100µlinPBS+10mMsodiumazide.
Forlongtermstorage–20°Cisrecommendedinundilutedaliquots.Stableat–20°Cforatleast1year.Avoidfreeze/thawcycles.
ProductSpecficReference
Kolisnyk,B.,Al-Onaizi,M.,Soreq,L.,Barbash,S.,Bekenstein,U.,Haberman,N., Hanin,G.,Kish,M.T.,daSilva,J.S.,Fahnestock,M.,Ule,J., Soreq,H.,Prado,M.A.,&Prado,V.F.(2016).CholinergicSurveillanceoverHippocampalRNAMetabolismandAlzheimer’s-LikePathology.CerebralCortex,bhw177. PMID:27312991
Kolisnyk,B.,Al-Onaizi,M.A.,Xu,J.,Parfitt,G.M.,Ostapchenko,V.G.,Hanin,G.,Soreq,H.,Prado,M.A.,&Prado,V.F.(2016).CholinergicRegulationofhnRNPA2/B1TranslationbyM1MuscarinicReceptors.TheJournalofNeuroscience,36(23),6287-6296.PMID:27277805
