Rabbitpolyclonalantibody

Size:

100µl

Formulation:

Affinitypurified

Specificity:

Rat,Mouse,Human,Bovine,Non-humanprimate,Sheep,Canine

Applications:

WB1:1,000IHC1:1,000

Species:

Rabbit

MolecularReference:

~110kDato~130kDa

CiteThisAntibody:

PhosphoSolutionsCat#p170-5359,RRID:AB_2492138

Storage

100µlin10mMHEPES(pH7.5),150mMNaCl,100µgpermlBSAand50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.

Forlongtermstorage–20°Cisrecommended.Stableat–20°Cforatleast1year.

ProductSpecificReferences

Zheng,H.,Qian,J.,Baker,D.P.andFuchs,S.Y.,2011.TyrosinephosphorylationofproteinkinaseD2mediatesligand-inducIBLeeliminationoftheType1interferonreceptor.JournalofBiologicalChemistry,286(41),pp.35733-35741. PMID:21865166

Qian,J.,Zheng,H.,HuangFu,W.C.,Liu,J.,Carbone,C.J.,Leu,N.A.,Baker,D.P.andFuchs,S.Y.,2011.Pathogenrecognitionreceptorsignalingacceleratesphosphorylation-dependentdegradationofIFNAR1.PLoSPathog,7(6),p.e1002065. PMID: 21695243

Bhattacharya,S.,Qian,J.,Tzimas,C.,Baker,D.P.,Koumenis,C.,Diehl,J.A.andFuchs,S.Y.,2011.Roleofp38proteinkinaseintheligand-independentubiquitinationanddown-regulationoftheIFNAR1chainoftypeIinterferonreceptor.JournalofBiologicalChemistry,286(25),pp.22069-22076. PMID: 21540188

BhattacharyaS,HuangFuWC,LiuJ,VeerankiS,BakerDP,KoumenisC,DiehlJAandFuchsSY.(2010)Inducibleprimingphosphorylationpromotesligand-independentdegradationoftheIFNAR1chainoftypeIinterferonreceptor.JBiolChem.285(4):2318-25.PMID: 19948722

Liu,J.,Carvalho,L.P.,Bhattacharya,S.,Carbone,C.J.,Kumar,K.S.,Leu,N.A.,Yau,P.M.,Donald,R.G.,Weiss,M.J.,Baker,D.P.andMcLaughlin,K.J.,2009.Mammaliancaseinkinase1αanditsleishmanialorthologregulatestABIlityofIFNAR1andtypeIinterferonsignaling.Molecularandcellularbiology,29(24),pp.6401-6412.PMID: 19805514

K.G.SureshKumar,JohnJ.Krolewski,andSergeY.Fuchs(2004)PhosphorylationandSpecificUbiquitinAcceptorSitesAreRequiredforUbiquitinationandDegradationoftheIFNAR1SubunitofTypeIInterferonReceptor.J.Biol.Chem.,Nov2004;279:46614–46620.PMID:15337770